Subscribe
Generic selectors
Exact matches only
Search in title
Search in content
Post Type Selectors
Man giving a dog medicine pill

The essentials

  • Tramadol is safe for dogs — If taken with vet supervision, tramadol can help manage your dog’s pain levels and improve their quality of life.
  • Doctors prescribe tramadol for human aches and pains — It’s one of the few human painkillers that is safe to give to dogs.
  • Tramadol is an opioid — Like most opioids, tramadol doesn’t treat the underlying cause of pain. Instead, it provides relief by altering the way the body perceives pain.

Tramadol at a glance

Medication type: analgesic (synthetic opioid)

Form: flavored chews, tablets, or liquid

Availability: Prescription only

Price: $10–$30 for a month’s supply, depending on dosage and quantity

FDA approved? Yes, but only for humans

Life stage: All life stages

Popular products/Common names: Ultram®, ConZip®, Durela®, Ralivia®, Rybix®, Ryzolt®, Tridural®,  Zytram®

Dosages: .45 to 1.8 mg per pound of body weight

Expiration range: 1–2 years when stored properly

🚨 Always check the expiration date on the packaging and avoid using any medication past its expiration date, as its effectiveness and safety may be compromised.

What is tramadol? 

Tramadol is a medication commonly prescribed to treat pain in humans and other small mammals like dogs. It’s a synthetic opioid that works by binding to the brain’s opioid receptors and altering the transmission and perception of pain. It also blocks the brain’s reuptake of norepinephrine and serotonin, creating a buildup of these chemicals in the bloodstream that causes overall feelings of calm and euphoria.

Since tramadol is mainly intended to treat humans, its use in veterinary medicine is considered off-label, but it’s perfectly safe for most dogs when taken under vet supervision. Tramadol isn’t as strong as some of the other drugs in the opioid family and often produces fewer side effects in dogs.

Drug interactions and tramadol

When giving your dog tramadol, it’s important to be aware of potential drug interactions. Here are some medications that should be used with caution or avoided altogether:

  • Antifungals (e.g., Ketoconazole)
  • Metoclopramide (Reglan)
  • Ondansetron (Zofran)
  • Other opioids (e.g., morphine, hydrocodone)
  • SAMe (s-adenosylmethionine)
  • Antidepressants (e.g., fluoxetine – Prozac)

Risk factors associated with tramadol

Tramadol should not be used in dogs that are hypersensitive to opioids, as it can cause severe reactions. It is also advised to avoid using tramadol in pregnant or nursing dogs, and those with a history of recent seizures or severe liver or kidney disease.

Here are some conditions where tramadol should be used with caution:

  • Seizure disorders
  • Liver disease
  • Kidney disease
  • Geriatric or debilitated dogs

Signs of a tramadol overdose

If a dog is given an incorrect dosage of tramadol, or if they get into a prescription that’s lying around, an accidental overdose can happen. These reactions are serious and should be treated by a vet as soon as possible. Symptoms of tramadol overdose include:

  • Respiratory depression
  • Decreased heart rate
  • Tremors or seizures
  • Excessive drooling
  • Sedation
  • Agitation
  • Dilated pupils
  • Ataxia (uncontrollable movement)
  • Loss of consciousness
  • Coma

What tramadol is used for in veterinary medicine

Tramadol is used to treat moderate to severe pain in dogs and cats, which could result from any of the following conditions:

  • Cancer
  • Osteoarthritis
  • Lameness/difficulty walking
  • Post-operation or post-surgery pain
  • Spinal diseases
  • Chronic pain
  • Anxiety

Like most opioids, tramadol doesn’t treat the cause of a dog’s pain. Tramadol simply makes them more comfortable by altering their perception of that pain. It also doesn’t treat inflammation, so it’s often used with other medications like nonsteroidal anti-inflammatory drugs, or NSAIDs.

Tramadol is most commonly given by mouth as a capsule, tablet, or liquid. The usual dosage for dogs is 0.45 to 1.8 milligrams (mg) per pound of their body weight every 8 to 12 hours, but this varies based on what type of pain your dog is experiencing, as well as any pre-existing conditions they may have. Always ask a vet to help you determine the best dose for your dog, and do not give them pills from human Tramadol prescriptions.

Side effects of tramadol

Tramadol is generally safe for dogs to take as long as the dosage instructions are followed properly, but there are still some side effects to look out for. These include:

  • Vomiting
  • Nausea
  • Dizziness
  • Lethargy
  • Tremors or seizures
  • Diarrhea
  • Anxiety

While every dog reacts to tramadol differently, you should contact your veterinarian if you notice any of these side effects. Tramadol is metabolized through the liver and kidneys, so it’s best to have a professional monitor these organs early on as a precaution.

Dosage information for tramadol

Tramadol is a controlled substance, meaning it requires a prescription from a veterinarian. This is to ensure that your dog receives the correct and safe amount of medication. Tramadol’s classification as a controlled substance also highlights its potential for misuse and the importance of careful handling.

Determining the correct tramadol dosage for your dog is a complex process that only a veterinarian can accurately perform. The dosage isn’t based solely on your dog’s weight; several factors are considered. These include your dog’s overall health, medical history, the type and severity of pain, and any other medications your dog may be taking.

Correct dosage of Tramadol is important in dogs to make sure they get enough of the medication to provide pain relief, but not too high of a dose which could lead to side effects.

Dr. Dwight Alleyne

It is crucial not to try and guess the dosage on your own. Incorrect dosing can lead to serious health risks, including overdose, which can have severe or even life-threatening consequences. Always consult your veterinarian for the appropriate prescription and dosage instructions tailored to your dog’s specific needs. This ensures your dog receives safe and effective pain management while minimizing the risk of adverse effects.

What to do if you miss a dose

If you miss giving your dog a dose of tramadol, give it as soon as you remember. However, if it’s almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give your dog two doses at once to make up for the missed dose, as this can increase the risk of side effects. Always follow your veterinarian’s instructions and contact them if you have any concerns about missed doses or your dog’s medication schedule.

Tramadol is a powerful medication and should only be used under the guidance of a professional. If your dog needs pain relief and you haven’t spoken to your vet, consult them about safe over-the-counter options to manage your dog’s pain until you can get a proper prescription. For more information about pain medications for dogs, explore our other articles and resources.

Frequently asked questions

Is gabapentin or tramadol better for dogs?

Tramadol is primarily used for managing moderate to severe pain and works as a synthetic opioid. Gabapentin, on the other hand, is often prescribed for chronic pain, nerve pain, and as an adjunctive treatment for seizures. Your veterinarian will consider your dog’s medical history, type of pain, and overall health before recommending the best option.

What’s the difference between dog tramadol and human tramadol?

Dog tramadol and human tramadol are essentially the same medication in terms of their active ingredient. However, the dosage and administration may differ significantly. Tramadol for dogs is often prescribed at higher doses relative to their body weight because dogs metabolize the drug differently than humans.

Will tramadol calm my dog?

While tramadol can be an effective anxiety medication for dogs, it’s also been known to cause anxiety as a side effect. Always consult a veterinarian about the correct medication and dosage for your dog’s anxiety.

Does tramadol work immediately for dogs?

Tramadol is a fast-acting drug that takes effect one to two hours after consumption.

How long does tramadol last for pain in dogs?

Tramadol is a short-acting medication that lasts about six to eight hours and fully wears off after about 24 hours.